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7.6 A Phase II Clinical Trial Testing Liraglutide in AD As a result of the neuroprotective effects of liraglutide that we observed in animal models of AD [193], we obtained funding for a randomized, placebo-controlled, double-blind phase II clinical trial testing liraglutide in 204 participants with mild AD (NCT01843075) (the ELAD study) [194]

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Moreover, YPF-PPG-neurons innervate ventral medullopontine catecholaminergic groups, including A1, A5, and C1 neurons, essential for regulating blood pressure and cardiovascular homeostasis [29,146,147]